Chalcones are aromatic ketones that form the central core for a variety of important biological compounds. Previous research in Dr. Calderón-Urrea’s laboratory showed the efficacy of eight chalcones (1, 16, 17, 18, 19, 22, 25, and 30) to kill Caenorha . . .

Chalcones are aromatic ketones that form the central core for a variety of important biological compounds. Previous research in Dr. Calderón-Urrea’s laboratory showed the efficacy of eight chalcones (1, 16, 17, 18, 19, 22, 25, and 30) to kill Caenorha . . .

Worldwide, there are 65 million people that have epilepsy and approximately 200,000 additional individuals are diagnosed with epilepsy annually. There is no cure and currently available anticonvulsants, which are medications to treat seizures, are not . . .

This study involved Drosophila melanogaster, the common fruit fly, as the model organism to study the behavioral differences seen in flies overexpressing the human tau protein throughout their adult life span. The tau protein (MAPT – microtubule ass . . .

The Escherichia coli cAMP receptor protein (CRP) requires both DNA binding and RNA polymerase recruitment for its transcriptional activation function. The DNA recognition of CRP is performed by the F-helix (residues 180-185) and several F-helix resi . . .

Bacteria must be able to withstand a myriad of stresses from both their environment, and in the case of pathogens, from their host. Low molecular weight thiols serve as redox buffers to maintain a reducing environment in the cell and participate in va . . .

Discovered in 2004, tunneling nanotubes (TNTs) are actin-based, bridge-like structures that allow the intercellular transport of cellular components, electrical signals, and pathogens. Thus, TNTs have been implicated in viral propagation, neurodegener . . .

Tunneling nanotubes (TNTs) have been recently discovered as an essential form of cell-cell communication in multicellular organisms. Although TNTs appear to be an important cell-cell signaling pathway, its mechanism of formation and functions are st . . .

Bacterial second messenger, c-di-GMP, regulates important functions such as biofilm formation, motility, and virulence. C-di-GMP also has an immunostimulatory property, so can be used as a vaccine adjuvant. In this project, DgcZ (a diguanylate cycla . . .

Clearcut logging of numerous small stands of trees over the last fifteen years has provided suitable areas for the study of early secondary plant succession on the western slope of the central Sierra Nevada mountains. Familiarity with early succession . . .