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- Creator:
- Carlin, Joseph A.
- Description:
- Extreme episodic events have the capacity to transport large amounts of terrestrial material to the coastal ocean. While estuaries and deltas are typically thought to trap most of this material, some escapes these coastal features and is transported to distal depocenters along the continental shelf. Distal shelf depocenters can act as the ultimate sink for event deposits, yet event sedimentation and the impact of terrestrial carbon burial within these shelf deposits remains understudied. Therefore, this study investigated event sedimentation within the Texas Mud Blanket (TMB), a distal shelf depocenter of the Brazos River located in the northwestern Gulf of Mexico. Using a core that was collected from the TMB during a months-long elevated discharge event in late 2015 to early 2016 we applied a multi-proxy approach to delineate the event deposit. We utilized physical sediment properties (fabric, texture, and bulk density), radioisotopes (7Be and 210Pb), and organic geochemical properties (ẟ13C, C/N, and lignin-phenols) to identify a 10 cm event layer at the surface of the core. Within this 10 cm layer, we also distinguished two sub-layers associated with separate extreme discharge periods in the winter and spring, respectively. Using these event layer characteristics, we identified three other earlier potential event deposits in the core that we have attributed to events in 2010, 2007, and 2000–2001. From these results, this study has demonstrated that the TMB may be an archive for event deposits over multi-decadal time periods, in particular the transition from periods of prolonged drought to extreme wetness associated with the Brazos River. This event-dominated sedimentation regime can enhance long-term carbon burial, potentially increasing current estimates of carbon burial significantly in the TMB and other similar distal shelf depocenters. Ultimately this study highlights the potential for distal shelf depocenters as organic carbon burial “hotspots,” and postulates that this role may expand in the future as climate change increases the intensity and frequency of extreme events.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Biological Sciences
- Creator:
- Paig-Tran, E.W. Misty, Lowe, Andrew, Walker, Sean, and Walter, Ryan P.
- Description:
- The cory catfishes (Callichthyidae) are small, South American armored catfishes with a series of dermal scutes that run the length of the fish from posterior to the parieto-supraoccipital down to the caudal peduncle. In this study, we explore the anatomy and functional performance of the armored scutes in the three-striped cory catfish, Corydoras trilineatus . The lateral surface has a dorsal and a ventral row of scutes that interact at the horizontal septum. The scutes have little overlap with sequential posterior scutes (~33% overlap) and a deep ridge in the internal surface that connects to the underlying soft tissue. The internal surface of C. trilineatus scutes is stiffer than the external surface, contrary to the findings in a related species of cory catfish, C. aeneus , which documented a hypermineralized, enamel-like, non- collagenous, hyaloine layer along the external surface of the scute. Clearing and staining of C. trilineatus scutes revealed that the scutes have highly mineralized (~50% mineralization) regions embedded in be- tween areas of low mineralization along the posterior margin. Puncture tests showed that posterior scutes were weaker than both anterior and middle scutes, and scutes attached to the body required 50% more energy to puncture than isolated scutes. Corydoras trilineatus has the strongest armor in areas critical for protecting vital organs and the external armored scute receives synergistic benefits from interactions to the soft underlying tissue, which combine to provide a tough protective armor that still allows for flexible mobility.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Biological Sciences
- Creator:
- Fisher, Koren
- Description:
- Introduction Sedentary behavior (SB) is highly prevalent among older adults, with more than 25% engaging in 6 hours or more of SB daily. SB has been associated with several cardiometabolic biomarkers in younger adults; however, there is a paucity of research in older populations. This study examined associations between patterns of SB and cardiometabolic biomarkers in community-dwelling adults aged 55 years and older. Methods Data were drawn from a convenience sample of 54 community-dwelling individuals (12 males, 42 females; mean age = 72.6 ± 6.8 years, range = 56–89 years). Cardiometabolic biomarkers assessed included systolic (SBP) and diastolic blood pressure (DBP), body mass index, waist circumference, and fasting blood glucose and cholesterol parameters. SB was assessed via accelerometry over a 7-day period, and measures included daily time in SB, number and length of sedentary bouts, the number and length of breaks between sedentary bouts, moderate-to-vigorous physical activity (MVPA), and light physical activity (LPA). Associations between the SB measures and each cardiometabolic risk factor were examined using separate stepwise multiple regression models, controlling for sex, MVPA, and accelerometer wear time. Isotemporal substitution models were used to examine the change in cardiometabolic outcomes when SB is replaced by an equal duration of either LPA or MVPA. Results Adjusted regression analyses showed that daily sedentary time was positively associated with DBP (β = 0.052, ∆R2 = 0.112, p = 0.022) and inversely associated with HDL cholesterol (β = −0.111, ∆R2 = 0.121, p = 0.039). Sedentary bout length was also associated with DBP and HDL cholesterol (β = 0.575, ∆R2 = 0.152, p = 0.007; β = −1.529, ∆R2 = 0.196, p = 0.007, respectively). Replacement of 10 minutes of SB a day with LPA was associated with improved DBP and HDL cholesterol (p ≤ 0.05). No other significant associations (p ≤ 0.05) were found. Conclusion Sitting for prolonged periods of time without interruption is unfavorably associated with DBP and HDL cholesterol. Prospective studies should identify causal relationships and observe specific changes in cardiometabolic profiles in older populations.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Kinesiology
- Creator:
- Lockie, Robert
- Description:
- There has been limited analyses of DI mid-major male basketball players, and no analyses of relationships between athletic abilities and playing time in this population. The purpose of this study was to (1) describe and compare backcourt and frontcourt players from one mid-major team and (2) determine if there were relationships between playing time (total minutes, total games played, minutes per game) and select tests from the NBA Combine (height, body mass, standing reach, and wingspan; countermovement [VJ] and approach [AppVJ vertical jump], lane agility drill, ¾ court sprint, and 83.91-kg bench press). A retrospective analysis of data from the 2018 season for a men's DI team (n = 10) was conducted. Performance testing was completed in the pre-season, and playing time metrics were collated by the team's staff over the season. Players were split into backcourt (n = 6) and frontcourt (n = 4) groups and compared via independent samples t-tests (p < 0.05) and effect sizes (d). Pearson's correlations calculated relationships between playing time metrics and the NBA combine test data (p < 0.05). When compared to the backcourt group, the frontcourt group were significantly taller, heavier, had a greater standing reach and wingspan, and performed poorer in the VJ, AppVJ, and ¾ court sprint (d = 1.49-3.45). There were no significant relationships between playing time and any NBA Combine test (r = -0.363-0.511). Basketball-specific skill may have a larger impact on playing time in this mid-major team. However, the mid-major players in this study may have had above-average athletic abilities as measured by NBA combine testing, limiting correlations with playing time.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Kinesiology
- Creator:
- Wu, Jindong
- Description:
- Urban trees provide various important ecological services, the quantification of which is vital to sustainable urban development and requires accurate estimation of tree biomass. A limited number of allometric biomass equations, however, have been developed for urban species due to the prohibitive cost. Remote sensing has provided cost-effective means for estimating urban forest biomass, although the propagation of error in the estimation process is not well understood. This study aimed to offer a baseline assessment of the feasibility of estimating urban tree biomass with remote sensing-based general equations applicable to broad taxonomic groups by conducting a large urban tree inventory on a university campus. The biomasses of 191 trees of seven species from the inventory, separated into two categories (i.e., evergreen and deciduous), were calculated exclusively with urban-based species-specific allometric equations. WorldView-2 satellite imagery data were acquired to retrieve normalized difference vegetation index (NDVI) values at the location, crown, and stand levels. The results indicated that biomass correlated with NDVI in varying forms and degrees. The general equations at the crown level yielded the most accurate biomass estimates, while the location-level estimates were the least accurate. Crown-level spectral responses provided adequate information for delivering spatially explicit biomass estimation.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Geography and the Environment
- Creator:
- Lee, Alice
- Description:
- Objectives: The aims of our study were to describe current hepatitis B prevalence among Vietnamese Americans and to examine predictors of hepatitis B risk in this specific ethnic community. Design: Cross-sectional analysis of data from a community-based screening program. Setting: This analysis was based on hepatitis screening community events in Southern California. Participants: 2508 Vietnamese Americans in Southern California. Outcome measures: Serological tests for hepatitis B surface antigen, hepatitis B surface antibody, and total hepatitis B core antibody were used to classify participants as one of four hepatitis B infection statuses: currently infected, previously infected, susceptible, or immune due to a previous hepatitis B vaccination. Results: Across 2508 participants, 9.0% were currently infected with hepatitis B and 17.7% were at risk for hepatitis B. Females and those reporting a previous hepatitis B vaccination were at significant decreased risk of hepatitis B (OR=0.48, 95% CI 0.33 to 0.69 and OR=0.53, 95% CI 0.31 to 0.93, respectively) whereas those born outside of the USA and with a family history of the disease showed substantial increased risk (OR=13.36, 95% CI 1.62 to 110.05 and OR=4.68, 95% CI 2.66 to 8.22, respectively). Among those who reported a previous hepatitis B vaccination, less than half (42.9%) possessed the protective antibodies that result from a hepatitis B vaccination. Conclusions: Vietnamese Americans remain disproportionately burdened by hepatitis B. Public health efforts that focus on improving hepatitis B awareness and vaccination knowledge and that are tailored to specific high-risk subgroups, such as immigrants and those with infected family members, could help in addressing the disease's burden in this high-prevalence population.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Public Health
- Creator:
- Carlin, Joseph
- Description:
- Continental shelf environments are uniquely situated to capture some of the most dynamic processes on Earth including climatic variability and anthropogenic modifications to coastal systems. Understanding how these processes have affected sediment delivery and accumulation on the shelf in the past may provide insight into potential changes in the future. To address this, we investigated shelf sedimentation within Monterey Bay, California. Sediment cores were collected from four locations throughout the bay to capture both the modern and late Holocene sedimentological record using grain size analysis, and sediment chronologies determined from 210Pb, 137Cs, and 14C. From the grain size results we focused on the total percent sand, and established a Littoral Sand Fraction (LSF) index to assess sediment contribution from the littoral zone as a result coastal erosion. Grain size results from the multicores consistently showed an increase in sand over the past several decades (post 1970s). For the cores located within the bay proximal to three major rivers, the increase in sand corresponded to a general increase in the LSF over the same period. We attributed these trends to increased sediment contributions to the shelf due to accelerated coastal erosion in the region. This accelerated coastal erosion was likely the combined result of dam construction in the mid-twentieth century that limited fluvial supply to the coast, and a shift in climate toward wetter, stormier period. Applying these sediment characteristics back over the past ∼1,000 years we found that dry climatic periods resulted in deposits that were limited in total sand but enriched in littoral material suggesting elevated coastal erosion. During wet periods deposits were enriched in total sand but limited in littoral sand suggesting elevated fluvial supply and low erosion. Compared to the late Holocene record, the previous several decades represent a shift to a new regime, uncharacteristic of deposits over the past millennia, highlighting the impact humans have had on shelf sedimentation.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Geological Sciences
- Creator:
- Yu Bai
- Description:
- During recent years, researchers throughout academia and industry have been advancing the theory, designing, and applications of mobile service computing through the Internet of Things (IoT). Research interest in mobile service computing stems from its performance, security, reliability, and power consumption. Hence, ultra-low power integrated circuits are essential for mobile service computing that can offer the advantages of low power for computational tasks in the IoT that is driven by the restricting constraints of power consumption and autonomy in both computation and idle phases. To attain the benefits of ultra-low power circuits, the energy-consuming and computational intense demands are imposed by the underlying processing and memory devices on which the conventional ultra-low power integrated circuit can benefit substantially from innovative hardware designs. Logic-in-Memory (LIM) architectures are considered as the potential approaches to attain goals within area and energy constraints starting with the lowest layers of the hardware stack. In this paper, we propose and implement the LIM asynchronous computing paradigm for energy-efficient mobile service computing. The results indicate that the proposed design achieves 38% leakage reduction and 30% accuracy improvement compared to the state-of-the-art non-volatile asynchronous circuits. At the system level, we compare our designs with various commercial microprocessors. The experimental results show that the asynchronous processors attain a four-fold throughput increase relative to their synchronous counterparts under these operating constraints. Therefore, the proposed design offers an approach toward tangible benefits of the battery-constrained embedded mobile service computing.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Computer Science
- Creator:
- Lockie, Robert
- Description:
- This study determined the influence of years spent working in custody on fitness measured by a state-specific testing battery (Work Sample Test Battery; WSTB) in deputy sheriffs. Retrospective analysis was conducted on one patrol school class (51 males, 13 females) divided into three groups depending on time spent working in custody: DS24 (<24 months; n = 20); DS2547 (25–47 months; n = 23); and DS48+ (≥48 months; n = 21). These groups were compared to a recruit class (REC; 219 males, 34 females) in the WSTB, which comprised five tasks completed for time: 99-yard (90.53-m) obstacle course (99OC); 165-pound (75-kg) dummy drag; six-foot (1.83-m) chain link fence (CLF) and solid wall (SW) climb; and 500-yard (457.2-m) run (500R). A univariate analysis of covariance (ANCOVA) (controlling for sex and age) with Bonferroni post hoc determined significant between-group differences. DS48+ were slower in the 99OC compared to the REC (p = 0.007) and performed the CLF and SW slower than all groups (p ≤ 0.012). DS24, DS2547, and DS48+ were all slower than REC in the 500R (p ≤ 0.002). Physical training should be implemented to maintain fitness and job-specific task performance in deputy sheriffs working custody, especially considering the sedentary nature of this work.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Kinesiology
- Creator:
- Kirby, Matthew
- Description:
- Records of past climate can inform us on the natural range and mechanisms of climate change. In the arid Pacific southwestern United States (PSW), which includes southern California, there exist a variety of Holocene records that can be used to infer past winter conditions (moisture and/or temperature). Holocene records of summer climate, however, are rare from the PSW. In the future, climate changes due to anthropogenic forcing are expected to increase the severity of drought in the already water stressed PSW. Hot droughts are of considerable concern as summer temperatures rise. As a result, understanding how summer conditions changed in the past is critical to understanding future predictions under varied climate forcings. Here, we present a c. 10.9 kcal BP δ18O(calcite) record from Lake Elsinore, California, interpreted to reflect δ18O(lake water) values as controlled by over-water evaporation from summer-to-early fall. Our results reveal three millennial scale intervals: (1) the highly evaporative Early Holocene (10.55–6.65 kcal BP), (2) the less evaporative Mid-Holocene (6.65–2.65 kcal BP); and (3) the evaporative Late Holocene (2.65–0.55 kcal BP). These results are coupled with an inferred winter precipitation runoff (sand content) record from Kirby et al. (2010). Using these data together, we estimate the duration and severity of centennial-scale Holocene droughts and pluvials (e.g., high δ18O(calcite) values plus low sand content = drought and vice versa). Furthermore, the coupled δ18O(calcite) and sand data provide a generalized Holocene lake level history. The most severe, long-lasting droughts (i.e., maximum summer-to-early fall evaporation and minimum winter precipitation runoff) occur in the Early Holocene. Fewer, less severe, and shorter duration droughts occurred during the Mid-Holocene as pluvials became more common. Droughts return with less severity and duration in the Late Holocene. Notably, the Little Ice Age is characterized as the wettest period during the Late Holocene.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Geological Sciences
- Creator:
- Loyd, Sean
- Description:
- Major hydrocarbon accumulations occur in traps associated with salt domes. Whereas some of these hydrocarbons remain to be extracted for economic use, significant amounts have degraded in the subsurface, yielding mineral precipitates as byproducts. Salt domes of the Gulf of Mexico Basin typically exhibit extensive deposits of carbonate that form as cap rock atop salt structures. Despite previous efforts to model cap rock formation, the details of subsurface reactions (including the role of microorganisms) remain largely unknown. Here we show that cap rock mineral precipitation occurred via closed-system sulfate reduction, as indicated by new sulfur isotope data. 13C-depleted carbonate carbon isotope compositions and low clumped isotope-derived carbonate formation temperatures indicate that microbial, sulfate-dependent, anaerobic oxidation of methane (AOM) contributed to carbonate formation. These findings suggest that AOM serves as an unrecognized methane sink that reduces methane emissions in salt dome settings perhaps associated with an extensive, deep subsurface biosphere.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Geological Sciences
- Creator:
- Galpin, Andrew
- Description:
- Human skeletal muscle fibers exist across a continuum of slow → fast-twitch. The amount of each fiber type (FT) influences muscle performance but remains largely unexplored in elite athletes, particularly from strength/power sports. To address this nescience, vastus lateralis (VL) biopsies were performed on World/Olympic (female, n = 6, “WCF”) and National-caliber (female, n = 9, “NCF”; and male, n = 6, “NCM”) American weightlifters. Participant accolades included 3 Olympic Games, 19 World Championships, 25 National records, and >170 National/International medals. Samples were analyzed for myosin heavy chain (MHC) content via SDS-PAGE using two distinct techniques: single fiber (SF) distribution (%) and homogenate (HG) composition. The main finding was that these athletes displayed the highest pure MHC IIa concentrations ever reported in healthy VL (23±9% I, 5±3% I/IIa, 67±13% IIa, and 6±10% IIa/IIx), with WCF expressing a notable 71±17% (NCF = 67±8%, NCM = 63±16%). No pure MHC IIx were found with SF. Secondary analysis revealed the heavyweights accounted for 91% of the MHC IIa/IIx fibers, which caused a correlation between this FT and body mass. Additionally, when compared to SF, HG overestimated MHC I (23±9 vs. 31±9%) and IIx (0±0 vs. 3±6%) by misclassifying I/IIa fibers as I and IIa/IIx fibers as IIx, highlighting the limitation of HG as a measure of isoform distribution. These results collectively suggest that athlete caliber (World vs. National) and/or years competing in the sport determine FT% more than sex, particularly for MHC IIa. The extreme fast-twitch myofiber abundance likely explains how elite weightlifters generate high forces in rapid time-frames.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Kinesiology
- Creator:
- Lockie, Robert
- Description:
- This study analyzed the effects physical fitness may have on reasons for academy separation in law enforcement recruits. A retrospective analysis was conducted on 401 recruits; 330 recruits graduated (GRAD), and 71 recruits separated at various times during academy. Twenty-eight recruits separated for personal reasons (SEPPR); 18 due to physical training failures (i.e., poor fitness) or injury (SEPFI); and 25 due to academic or scenario failures (SEPAS). Fitness testing occurred prior to academy, and included: Push-ups and sit-ups in 60s; a 75-yard pursuit run (75PR); vertical jump; medicine ball throw; and multistage fitness test (MSFT). A one-way ANOVA with Bonferroni post hoc compared between-group fitness test performance. A multiple stepwise regression calculated whether recruit characteristics or fitness could predict separation. The GRAD group was younger than the SEPAS group (p < 0.01), faster in the 75PR than the SEPFI group (p = 0.02), and completed more MSFT shuttles than the SEPPR and SEPFI groups (p = 0.01). Age predicted GRAD and SEPAS group inclusion; MSFT predicted GRAD, SEPPR, and SEPFI group inclusion. Recruits who had superior high-intensity running capacity (75PR) and aerobic fitness (MSFT) should have a better chance of completing academy. However, this could be influenced by training practices adopted during academy.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Kinesiology
14. The Role of Regional Contrast Changes and Asymmetry in Facial Attractiveness Related to Cosmetic Use
- Creator:
- Peissig, Jessie
- Description:
- This study collected behavioral data for testing how regional contrast changes due to the addition of cosmetics would affect attractiveness ratings. In addition, we used an established model of asymmetry to look for a correlation between changes in attractiveness related to the application of cosmetics to specific regions of the face and changes in symmetry. Using this asymmetry model we compared female faces with and without makeup. Specifically, we used a highly controlled set of grayscale faces in which makeup application was standardized to explore these issues from a perceptual perspective. The human data showed that adding upper eye makeup significantly increased attractiveness ratings. In contrast, increases in contrast to the lower eyes and lips did not lead to increases in attractiveness ratings; application of cosmetics to the lower eyes led to a significant decrease in attractiveness. We found that for the makeup condition that led to increased attractiveness, asymmetry did not change significantly when makeup was applied to the female faces. This suggests a role for mechanisms other than symmetry related to increases in attractiveness related to makeup use in females.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Psychology
- Creator:
- Tomaszewski, Robert
- Description:
- Identifying research gaps and generating research questions are often a first step in developing ideas for writing a research paper or grant proposal. The concept of substance-based bibliometrics uses the counts of substances in the scientific literature to better understand, assess, and clarify the state and impact of information in the chemical sciences. Connecting substances indexed to specific bioactivity or target indicators can lead to assessing the biochemical, biological, and medicinal relevance of substances as well as developing ideas for expanding drug design and discovery through identifying and modifying the structural features of molecules. This study uses Chemical Abstracts through the SciFinder database to count for the occurrence of substances in the scientific literature. The study sets out search strategies for discovering potential research gaps and new ideas through visualization of chemical structures with known bioactivity and target indicators. The author recommends that subject librarians integrate research gap training in their bibliographic instruction classes, particularly to upper-level undergraduate and graduate chemistry students.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Pollak Library
- Creator:
- Lockie, Robert
- Description:
- This study determined relationships between an agency-specific fitness test battery (PT500), and a work sample test battery (WSTB) in law enforcement recruits. Retrospective analysis on 219 males and 34 females from one agency was conducted. The PT500 comprised: push-ups, sit-ups, and mountain climbers in 120 s; pull-ups; and 201 m and 2.4 km runs. The WSTB comprised: 99 yard (90.53 m) obstacle course (99OC); body drag (BD) with a 165 pound (75 kg) dummy; 6 foot (1.83 m) chain link fence (CLF) and solid wall (SW) climb; and 500 yard (457.2 m) run (500R). Partial correlations, controlling for sex, calculated PT500 and WSTB relationships (p < 0.05). Stepwise regression determined whether fitness predicted WSTB performance. The 500R related to all PT500 assessments (r range = -0.127⁻0.574), 99OC related to all bar push-ups and mountain climbers, and BD related to none. The CLF related to sit-ups, pull-ups, and 2.4 km run; SW related to mountain climbers, pull-ups, and 2.4 km run (r range = -0.127⁻-0.315). Push-ups, pull-ups, and 2.4 km run were involved in predictive relationships for 99OC, CLF, SW, and 500R (r² range = 0.217⁻0.500). To perform better in the WSTB and job-specific tasks, developing upper-body strength and aerobic fitness may be beneficial.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Kinesiology
- Creator:
- Ramirez, Maria Soledad
- Description:
- Acinetobacter baumannii is a multidrug resistant nosocomial pathogen that shows an outstanding ability to undergo genetic exchange, thereby acquiring different traits that contribute to its success. In this work, we identified genetic features of an indigo-pigmented A. baumannii strain (Ab33405) that belongs to the clonal complex CC113B/CC79P. Ab33405 possesses a high number of genes coding for antibiotic resistance and virulence factors that may contribute to its survival, not only in the human host, but also in the hospital environment. Thirteen genes conferring resistance to different antibiotic families (trimethoprim, florfenicol, β-lactams, aminoglycosides and sulfonamide) as well as the adeIJK genes and the capsule locus (KL) and outer core locus (OCL) were identified. Ab33405 includes 250 unique genes and a significant number of elements associated with Horizontal Gene Transfer, such as insertion sequences and transposons, genomic islands and prophage sequences. Also, the indigo-pigmented uncommon phenotype that could be associated with the monooxygenase or dioxygenase enzyme coded for by the iacA gene within the iac cluster was probably conferred by insertion of a 18-kb DNA fragment into the iacG gene belonging to this cluster. The Ab33405 genome includes all type VI secretion system genes and killing assays showed the ability of Ab33045 to kill Escherichia coli. In addition, Ab33405 can modulate susceptibility antibiotics when exposed to blue light.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Biological Sciences
- Creator:
- James, Sagil
- Description:
- Dye-Sensitized Solar Cells (DSSC) are third generation solar cells used as an alternative to traditional silicon solar cells. DSSCs are characterized by their durability, easy handling and ability to perform better under diverse lighting conditions which makes them an ideal choice for indoor applications. However, DSSCs suffer from several limitations including low efficiencies, susceptibility to electrolyte leakage under extreme weather conditions, and the need for expensive materials and fabrication techniques which limits their large-scale industrial applications. Addressing these limitations through efficient design and manufacturing techniques are critical in ensuring that the DSSCs transform from the current small-scale laboratory levels to sizeable industrial production. This research attempts to address some of these significant limitations by introducing the concepts of nature-inspired fractal-based design followed by the additive manufacturing process to fabricate cost-effective, flexible counter electrodes for DSSCs. The new conceptual fractal-based design counter electrodes overcome the limitations of conventional planar designs by significantly increasing the number of active reaction sites which enhances the catalytic activity thereby improving the performance. The fabrication of these innovative fractal designs is realized through cost-effective manufacturing techniques including additive manufacturing and selective electrochemical co-deposition processes. The results of the study suggest that the fractal-based counter electrodes perform better than conventional designs. Additionally, the fractal designs and additive manufacturing technology help in addressing the problems of electrolyte leakage, cost of fabrication, and scalability of DSSCs.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Mechanical Engineering
- Creator:
- Ahmed, Wylie
- Description:
- The intracellular environment is a dynamic space filled with various organelles moving in all directions. Included in this diverse group of organelles are vesicles, which are involved in transport of molecular cargo throughout the cell. Vesicles move in either a directed or non-directed fashion, often depending on interactions with cytoskeletal proteins such as microtubules, actin filaments, and molecular motors. How these proteins affect the local fluctuations of vesicles in the cytoplasm is not clear since they have the potential to both facilitate and impede movement. Here we show that vesicle mobility is significantly affected by myosin-II, even though it is not a cargo transport motor. We find that myosin-II activity increases the effective diffusivity of vesicles and its inhibition facilitates longer states of non-directed motion. Our study suggests that altering myosin-II activity in the cytoplasm of cells can modulate the mobility of vesicles, providing a possible mechanism for cells to dynamically tune the cytoplasmic environment in space and time.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Physics
- Creator:
- Yang, Joshua
- Description:
- Background In response to the growing awareness and use of electronic nicotine delivery systems (ENDS), or e-cigarettes, the U.S. Food and Drug Administration asserted its regulatory authority over ENDS in May 2016. Federal, state, and local regulatory action on ENDS may have significant and unique impacts on specialty ENDS retailers, including tobacco and vape shops. The purpose of this study is to describe the commercial motivations of vape shops in minority communities as business entities whose financial interests and actions may be particularly impacted by regulation of ENDS. Methods Specialty tobacco and vape retail stores in three minority communities were identified through an online search and community canvassing. Key informant interviews were conducted with tobacco and vape shop owners or managers discussing the business interests and tactics of selling ENDS for their store. Interview data were coded and analyzed for major themes. Results Interviews with 18 tobacco shops and 9 vape shops were completed. Tobacco shops’ reasons for carrying e-cigarettes were business oriented, focused on maintaining their customer base. In comparison, vape shops opened because of the owner’s positive experiences with e-cigarettes and belief in the potential of e-cigarettes to help people quit or reduce smoking. Tobacco shops mainly see their customers as using e-cigarettes to quit smoking whereas vape shops reported their customers using e-cigarettes for more varied reasons. Tobacco shops are much more limited in their marketing than vape shops, which rely heavily on social media and experimentation with other forms of marketing. Conclusions Tobacco shops and vape shops differ in their rationale and approaches to the business of e-cigarettes. Vape shops engage in a wide range of activities that stabilize their financial interest and increase their influence with customers and within the vape community. In order for regulatory policymaking and tobacco control interventions to maximize effectiveness, the actions of vape shops in promoting ENDS use and influencing policy debates must be taken into account.
- Resource Type:
- Article
- Campus Tesim:
- Fullerton
- Department:
- Department of Public Health
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