Filtering by: Creator Friedlein, Jordan Bradley Remove constraint Creator: Friedlein, Jordan Bradley
ThesisThe Role of N-Terminal Domain Exposure of Bax in the Regulation of Intrinsic Apoptosis at the MitochondriaFriedlein, Jordan BradleyThe Bcl-2 protein family, made up of pro and anti-apoptotic proteins plays a major role in regulating apoptosis. Bax is a pro-apoptotic member of the Bcl-2 family. In its inactive form, Bax is primarily a cytosolic and monomeric protein. Upon activati . . .