The discovery of antitoxins to both diphtheria and tetanus toxins dramatically introduced two immunological phenomena to twentieth-century science. First, biologically active molecules, such as toxins and enzymes, may have the potential to be neutr . . .

Xylem is a complex vascular tissue that performs several functions related to the growth and survival of woody plants. These functions include the transport of water, biomechanical support, and the storage of water and nutrients. Trees are large organ . . .

Sculpins of the genus Cottus are commonly found in brackish water and streams of the Pacific drainage of North America (Morris, 1961). Though common, they are infrequently encountered being small, bottom dwelling fish, rarely exceeding 1 50 mm S. . . .

Global-change-type drought has resulted in large numbers of woody plants suffering mortality in California during the most recent droughts from 2012-2018. These droughts are ecological droughts that impact ecosystems and trigger responses. The factors . . .

Sandy beaches support dynamic and diverse, but physically narrow intertidal ecosystems that are vulnerable to the effects of anthropogenic disturbance, such as coastal dredging and beach nourishment. Our study site in Morro Bay, California has been . . .

Fewer than 40% of students that pursue college degrees in Science, Technology, Engineering, and Mathematics (STEM) do not graduate with a STEM degree. The rate of college degree attainment in STEM is about 20% lower for women, people with disabiliti . . .

Invasive annual grasses of mediterranean origin dominate large areas in the arid and semi-arid regions of the San Joaquin Valley in California and create numerous management challenges. Much of the invaded habitat would be native saltbush shrub commun . . .

Bladderworts, aquatic carnivorous plants, use specialized traps (with a mouth opening of about 0.2 mm in diameter) to complete their feeding strike in less than a millisecond after the trap begins to open. Suction feeding is well understood in animals . . .

Coccidioidomycosis, also known as Valley Fever, is a re-emerging infectious disease of the American continent. Coccidioidomycosis is a respiratory disease caused by the inhalation of arthroconidia produced by the dimorphic ascomycete fungi Coccidioide . . .

In order to further investigate the presence of these antibiotic biosynthetic pathways, this study focused on ten genes and the identification of genes that code for enzymes in these antifungal and antibacterial pathways; Flagellin (hag), Mucosubtilin . . .

My results suggest that Desert Kit Foxes in the Mojave Desert in California prefer to consume rodents and invertebrates, but will prey upon a variety of other items, especially when preferred prey has declined due to drought or seasonal conditions. O . . .

Three out of five wild populations and a laboratory- population of Indian meal moth, Plodia interpunctella (Hubner), were found resistant to malathion. A malathion-susceptible Indian meal moth population, stressed with malathion, showed a 110-fo . . .

The subject of this study, Peromyscus boylei (the brush mouse), is found from "Honduras northward to Oregon and Utah and eastward to the Ozark Mountains" (Hooper, 1968: 50). In California, it is found characteristically in the Upper Sonoran life zo . . .

Microsporangial development in angiosperms is a well documented process. In contrast, difficulties such as availability of material, prolonged development, and problems in sectioning have made information concerning microsporogenesis in gymnosper . . .

Chemicals are often sequestered by various organisms to defend against predators by making prey noxious, and in some cases, toxic. Sequestration has been observed in various taxa, however, there are few vertebrate examples available. Further, little i . . .

Mountain meadows offer aesthetic values and provide feed for cattle and wildlife, making it important for both financial and recreational reasons that they be maintained at maximum productivity. At the present, little is known about vegetation str . . .

The western foothills of the Sierra Nevada are dotted with small earthen reservoirs which are maintained by landowners primarily as a source of water for livestock. Most of these farm ponds have been stocked with warmwater gamefish such as largemou . . .

new concept in medical bacteriology was opened for investigation in 1935 when Kleinberger reported she had successfully separated a cell wall deficient variant from a normal culture of Streptobacillus moniliformis (Kleinberger, 1935). Kleinberger den . . .

The effects of two mammalian viruses (SV40 and reovirus) were observed on a homeothermic and on a poikilothermic cell line. Propagation of these viruses in both types of cells could indicate shared biochemical receptor sites on the two types of ce . . .

An estuary is a coastal area where river water meets oceanic water. A characteristic of a tidal estuary is brackish water which shows fluctuations in salinity. These fluctuations are due to the diurnal periodicity of the tide and the influx of fresh w . . .

Chromosomes were analyzed from the mitotic bone marrow of nine mountain pocket gophers (Thomomys monticola J. A. Allen, 1893). All the specimens, collected from three different localities in the'Sierra Nevadas, had a diploid number (2N) of 40. Ani . . .

There has been some uncertainty regarding the subspecific variation, distribution, and resultant taxonomy Dipodomys nitratoides. It was the purpose of this study to critically examine the geographic variation of this species and, on the basis of t . . .

No Abstract or Summary.

This pilot study was designed to test the null hypothesis that tnere is no significant difference between the information obtained by the indigenous Mexican Health Worker on the initial visit to a Mexican patient and that obtained by the professional . . .

It has been reported by Chew (1965) that all pathways of water exchange are reduced when mammals are subjected to dehydration. With few exceptions, evaporation is the major loss, and usually the greatest absolute conservation of water is realized . . .

The structure of intermittent streams has been described by Abell (1956) . Her work was based on the analysis of Dry Creek, Fresno County, California, which she considered a typical intermittent stream. An earlier work (Stehr and Bransen, 1938) ha . . .

Probiotics are live microorganisms that provide therapeutic effects to their consuming host’s gastrointestinal tract and immune system. Although they are considered “generally recognized as safe” (GRAS) by the FDA and are added to a plethora of prob . . .

Pseudomonas aeruginosa is an opportunistic pathogen that commonly causes serious nosocomial infections. P. aeruginosa’s virulence is derived from its large genome that allows adaptations to many environments and high antibiotic resistance. Gene sequ . . .

Inauguration of the embryonic development of the vertebrate nephros begins within the cranial reaches of the intermediate mesoderm. The anterior portions of this mesoderm give rise to the nephrotomes which are the forerunners of the first nephrons . . .

Faculty and students of the Moss Landing Marine Laboratory, Moss Landing, California, have been conducting population studies of the dorid nudibranchs in the intertidal of the Monterey Peninsula, California, since 1969. Throughout the studies two c . . .

The Nematode suborder Strongylata is among the most important groups of nematodes to man. In addition to two species of hookworms which infect millions of people in the world today, some 40 species of Strongyles infect domestic animals, causing co . . .

Intestinal nematodes of the family Heligmosomidae have been the subject of investigation for many years. Perhaps, the best studied species in the family has been Heligmosomoides polygyrus (Dujardin, 1845) (Nematospiroides dubius Baylis, 1926). Alt . . .

A population of three-spined sticklebacks Gasterosteus aculeatus L. from the San Joaquin River below Friant Dam near Fresno, California, was found to be infected with the plerocercoid larval stage of a pseudophyllidean cestode, Schistocephalus sol . . .

The L-Form of Staphylocoecus aureus is of interest from a clinical point of view since it has been often associated with certain diseases. S- aureus L-Forms have been isolated from recurrent osteomyelitis (Rosner, 1968)., In addition, Kagan (1972) . . .

The germination of asexual spores of most fungi requires a suitable substrate and a compatible environment. Heat-induced macroaleuriospore germination in Microsporum gypseum has been studied previously by Leighton and Stock (1968). They mentione . . .

Captive breeding is a critical management strategy in the recovery and preservation of certain threatened and endangered species. Programs that implement captive breeding must maintain a balance between preserving the genetic purity and genetic dive . . .

Formation of endospores by aerobic bacilli serves as a model system for answering basic questions related to development and cyto- differentiation in general. An important aspect of sporulation is that different bacilli seem to form spores by g . . .

This study was undertaken to investigate seasonal acclimatization in two populations of Hyalella azteca as measured by their oxygen consumption. One population was taken from a high Mg habitat and one from a low Mg environment. No significant seasonal . . .

Taxonomic and general natural history studies have been complemented by physiological and energetic considerations. This additional emphasis is necessary if the functional role that each species plays in the ecosystem is to be determined. To ascer . . .

This research project bears upon a number of fields of study, including physiology, biochemistry and psychopathol- ogy. The experiment was designed to create an altered behavioral state by the stress of sensory deprivation. The altered behavioral . . .

Penicill ium exnansum is a common fungus occurring in the organic debris in soil. It can also be found in food products, such as grains, cereal products, eggs and chickens (Raper and Thorn, 194-9). However, it is most common in ripe fruits suc . . .

When pasture land, is grazed by cattle the composition of the herbaceous vegetation is changed from that of the ungrazed state and the ecology of the pastoral habitat will be variously affected. The object of this investigation was to examine the dist . . .

Declining trout harvests in rivers on the west slopes of the Sierra Nevada constitute a major fishery management problem in California. As part of a research team investi- gating this problem in the Kings River, my research consisted of docume . . .

Xylella fastidiosa is a xylem-obligate plant pathogenic bacterium that causes disease in diverse crop plants. In grapevines, the infection is known as Pierce’s disease, which is limited to regions with warmer climates and fails to appear in cold cli . . .

The primary emphasis in most studies of bacteria and the relationship they have with their host is directed at the study of pathogenic species and the diseases caused by them, However, in addition to the pathogenic bacteria, there are many bacteria . . .

The San Joaquin kit fox (Vulpes macrotis mutica) is an endangered species endemic to the San Joaquin Desert in the Central Valley of California. Much of the habitat in the San Joaquin Desert has been converted for agricultural, industrial, and urban d . . .

The California State Park system, hereafter referred to as CalDPR, has sought for five years to include Carmel Bay, California, in its park system as an underwater park. Carmel Bay is approximately 15 km (5 mi ) in area, located between Pescadero Poin . . .

An important aspect of any group of organisms from both ecologic and evolutionary points of view is the part played by that group in channeling the flow of energy within the community in which it lives. Foraminifera, marine protozoans with calcium car . . .

The primary purpose of this study was to-investigate the feeding habits of silversides (Family Atherinidae) in Elkhorn Slough, Monterey Bay, California, since little detailed work on the feeding habits of silversides from California has been pub . . .

Russian Peak, at an elevation of 8200 feet, is situ­ated in the Salmon Mountains, a north-south trending range centrally located within the Klamath Region of northwest­ern California. The Salmon Mountains are drained by the Scott River on the east and . . .

Clearcut logging of numerous small stands of trees over the last fifteen years has provided suitable areas for the study of early secondary plant succession on the western slope of the central Sierra Nevada mountains. Familiarity with early succession . . .

Six species of Simulium larvae found in the Kings River near Piedra, Fresno County, California, are described. The black fly larvae and pupae were reared in the laboratory for taxonomic association of the immature instars, the pupae and the adults. . . .

Nitidulid beetles have been recognized as major pests of figs In California since 1900 (Simmons et al., 1931). Early workers were concerned primarily with Carpophllus hemlpterus (Linnaeus), the dried-fruit beetle, as the principal nitidulid pest ( . . .

The natural history of the Fresno kangaroo rat, Dipodomys nitratoides exilis, in the San Joaquin Valley's alkali sink habitat was first described by Culbertson (1946). His study included little information on the interspecific interactions with ot . . .

The field of membrane investigation is over 80 years old. Yet that remarkably complex and diverse structure, the cell membrane, continues to elude precise definition of structure and function. Observers have found cell membranes to be involved . . .

The rate of growth of catfish farming in the United States during the past 16 years is. unequalled in the history of fish culture. Commercial production of channel catfish (Ictalurus punctatus) has increased from its beginnings in 1960 to an estim . . .

The presence or absence of intestinal parasites in a human population is one indication of the quality of life the people lead. Particularly, human intestinal helminths and protozoans have been used to indicate the sanitary standards of a populatio . . .

Shortly after the discovery of the role of bacteria as the etiological agents of human disease, the search for bacterial toxins began. Bacterial toxins were an important discovery, because they may enhance the pathogenicity of infection; the effect of . . .

Previous work on the North Kings deer herd has shown that the reproductive potential of the does was high; however, there was a 50 percent neonatal loss of fawns. The neonatal loss was hypothesized to be the result of a nutritional stress expe . . .

Ranch ponds are numerous in the foothills of the western Sierra Nevada. An article appearing in the California Cattleman (anon, 1975) estimated that there were more than 50,000 ponds of less than 0.0123 cubic hectometers (10 acre feet) in California. . . .

Two hemipterans, Oncopeltus fasciatus Dallas (Lygaeidae) and Leptocoris trivittatus Say (Corizidae) (Feir, 1974; Woolley, 1949), have been used extensively in research and teaching due to availability and/or ease of rearing. The common squash bug, . . .

Waters containing enteropathogenic microorganisms (i.e., Salmonella, Shigella) are considered unsafe for human consumption. Traditionally, indicator bacteria have been utilized for the assess- ment of bacteriologically unsafe waters. However, a d . . .

Meso-American squirrel monkeys (Saimiri sciureus), restricted to the narrow coastal zone of southeastern Costa Rica and southwestern Panama, are widely separated from their conspecifics east of the Andes, and have a more reduced range than indicate . . .

Bush Anemone (Carpenteria californica Torr.) is a rare endemic shrub that exists within a limited range in Eastern Fresno County, California. Little floristic or vegetation research has been conducted on the species in its natural environment. The . . .

Following the methods of Gardner and Gardner (1969) and Premack and Premack (1972), others have continued human- pongid two-way communication studies elaborating upon the procedures of both the former investigators. Fouts (1973), after the Gar . . .

Farm ponds are small man-made resevoirs used for watering of farm animals, irrigation and fishing. Because of their small size, farm ponds are susceptible to rapid eutrophication which can cause growth of noxious or poisonous algae, unpleasant odor . . .

This three year study (1970-1972) was undertaken to document reproductive success in a colony of great blue herons at the San Joaquin River Heronry, Merced County, California. Quantitative data were collected on incubation period, clutch size, ha . . .

Bacterial second messenger, c-di-GMP, regulates important functions such as biofilm formation, motility, and virulence. C-di-GMP also has an immunostimulatory property, so can be used as a vaccine adjuvant. In this project, DgcZ (a diguanylate cycla . . .

In most temperate coniferous forests, the vast majority of vascular plant species richness can be found in the understory layer. While the large-scale conversion of forests to plantations has made it increasingly important to understand how understory . . .

The Blainville's Horned Lizard (Phrynosoma blainvillii) is endemic to California and ranges from northern California (Butte County), to the northwestern tip of Baja California in the southern part of its range, west of the Sierra Nevada Mountains and . . .

The purpose of this study is to compare the genetic distances of Mimetus hesperus and Theridion neomexicanum within and between the San Joaquin Valley and Mojave Valley regions. To my best knowledge this is the first genetic study of M. hesperus. Moun . . .

All zoos grapple with challenges of keeping captive animals engaged in natural behaviors, especially for bears which prove to be among the more challenging species to keep stimulated. In captivity, a common indicator of poor welfare is the presence . . .

Purpose of the Study: Understanding impacts of invasive pathogens and wildfire on forests is a major challenge facing scientists, land managers, and policymakers. In this study, I used a long-term plot network in eastern Sonoma County to disentangle t . . .

Tunneling nanotubes (TNTs) have been recently discovered as an essential form of cell-cell communication in multicellular organisms. Although TNTs appear to be an important cell-cell signaling pathway, its mechanism of formation and functions are st . . .

Discovered in 2004, tunneling nanotubes (TNTs) are actin-based, bridge-like structures that allow the intercellular transport of cellular components, electrical signals, and pathogens. Thus, TNTs have been implicated in viral propagation, neurodegener . . .

Purpose of the Study: California black oak, Quercus kelloggii, plays an important role in the lifeways of many indigenous tribes throughout California. Native peoples tend black oaks using Traditional Ecological Knowledge (TEK) to encourage the devel . . .

Bacteria must be able to withstand a myriad of stresses from both their environment, and in the case of pathogens, from their host. Low molecular weight thiols serve as redox buffers to maintain a reducing environment in the cell and participate in va . . .

The Escherichia coli cAMP receptor protein (CRP) requires both DNA binding and RNA polymerase recruitment for its transcriptional activation function. The DNA recognition of CRP is performed by the F-helix (residues 180-185) and several F-helix resi . . .

Worldwide, there are 65 million people that have epilepsy and approximately 200,000 additional individuals are diagnosed with epilepsy annually. There is no cure and currently available anticonvulsants, which are medications to treat seizures, are not . . .

The perciform suborder Notothenioidae is comprised of Antarctic and sub-Antarctic fishes, several of which have lost their ability to rapidly upregulate major heat shock proteins (HSP’s) in response to thermal stress. In fact, some notothenioid spec . . .

This study involved Drosophila melanogaster, the common fruit fly, as the model organism to study the behavioral differences seen in flies overexpressing the human tau protein throughout their adult life span. The tau protein (MAPT – microtubule ass . . .

Purpose of the Study: To understand male and female mate choice patterns affecting species and gender recognition via long distance chemical cues, this study examined the rough skin newt, Taricha granulosa, in both pond and creek habitats. Response to . . .

Hamadryas baboons (Papio hamadryas) live in a complex multilevel social system with the one-male-unit (OMU) at the core. OMUs consist of an adult alpha male with one or several adult females, their dependent offspring and sometimes a few follower male . . .

Purpose of the study: Adipose tissue is essential to endotherms for thermal regulation and energy storage as well as functioning as an endocrine organ. Adipose derived hormones, or adipokines, regulate metabolism, energy expenditure, reproduction, and . . .

Purpose of the Study: Long-lived iteroparous females may suppress reproduction during unfavorable conditions to maximize lifetime reproductive success. Capital breeders must accrue sufficient body reserves to support reproductive effort or they may ex . . .

Purpose of the Study: The Russian River watershed stretches across a significant portion of Sonoma and Mendocino counties, covering 1,485 square miles, and is home to not only humans, but countless fish and wildlife species as well. The Russian River . . .

Transporting water efficiently is one of the chief functions of plant vascular systems. Highly efficient transport is generally beneficial; however, tradeoffs arise because vascular systems have multiple functional roles that interact with one another . . .

Ecological interactions can vary in strength depending on environmental conditions. The outcomes of these interactions are often dependent on the abiotic environment, but can also depend on the presence of other biotic species, including mutualists, . . .

Research on animal movement patterns and factors that influence these patterns is vital to conservation of endangered species. The California Red-legged frog (Rana draytonii) is a threatened species native to California. Their rapid decline has been l . . .

Non-native grass invasion is a major concern for land management and native plant conservation. In the southern San Joaquin Valley of California, human-disturbed environments that are heavily invaded by non-native grasses often contain some native ann . . .

Examination of fish skeletal remains from archaeological sites serves both archaeological and biological interests. For archaeologists, it can establish the role of fish consumption in a people’s diet, provide clues to their fishing technology and ove . . .

The Giant Kangaroo Rat (Dipodomys ingens) is a federally and state-listed endangered species, endemic to the San Joaquin Valley, Carrizo and Elkhorn Plains, and the Cuyama Valley. Populations of the endangered Giant Kangaroo Rat (Dipodomys ingens) hav . . .

Opuntia basilaris Engelm. & Bigelow var. treleasei (J.M. Coult.) Toumey (OBT), commonly known as Bakersfield cactus, is endemic to parts of Kern County, California. O. b. var. treleasei is one of four varieties of Opuntia basilaris and is state and fe . . .

The purpose of this study is to investigate the level of genetic divergence among populations of Vaejovis confusus in the southern San Joaquin Valley and across the state of California. Although there has been considerable research to measure genetic . . .

The phorid fly genus Apocephalus is the largest assemblage of ant-parasitizing Phoridae. Apocephalus is currently organized into two subgenera: A. (Apocephalus) and A. (Mesophora). The species of A. (Mesophora) attack a wide variety of non-ant hosts i . . .

With over 1,300 known species, the genus Megaselia Rondani is the largest phorid genus, largely the result of high cryptic diversity and a past tendency for researchers to lump species into the genus that defied convenient classification. For many of . . .

Rhus ovata is an evergreen shrub species that is common to low elevations in southern California. This species is subdioecious, i.e. some individuals are functionally females and produce fruit while others are functionally male and produce flowers wit . . .

Purpose of the Study: The endangered Sonoma County population of the California tiger salamander, Ambystoma californiense, undergoes migrations between breeding pools and upland dry-season refugia. Orientation in this species during breeding migration . . .

The Tipton kangaroo rat (Dipodomys nitratoides nitratoides), is an endangered subspecies of the San Joaquin Valley kangaroo rat, found in the Tulare basin of the San Joaquin Valley. Dipodomys n. nitratoides and the larger Heermann’s kangaroo rat (Dipo . . .

The blunt-nosed leopard lizard (Gambelia sila) is a federally and state-listed endangered species, endemic to the San Joaquin Valley, Carrizo and Elkhorn Plains, and Cuyama Valley of central California. Habitat degradation has had a profound impact on . . .