Bacteria must be able to withstand a myriad of stresses from both their environment, and in the case of pathogens, from their host. Low molecular weight thiols serve as redox buffers to maintain a reducing environment in the cell and participate in va . . .

The Escherichia coli cAMP receptor protein (CRP) requires both DNA binding and RNA polymerase recruitment for its transcriptional activation function. The DNA recognition of CRP is performed by the F-helix (residues 180-185) and several F-helix resi . . .

Worldwide, there are 65 million people that have epilepsy and approximately 200,000 additional individuals are diagnosed with epilepsy annually. There is no cure and currently available anticonvulsants, which are medications to treat seizures, are not . . .

The perciform suborder Notothenioidae is comprised of Antarctic and sub-Antarctic fishes, several of which have lost their ability to rapidly upregulate major heat shock proteins (HSP’s) in response to thermal stress. In fact, some notothenioid spec . . .

The homocystinurias are a group of autosomal recessive disorders which are caused by various inborn errors of metabolism. Tnese disorders are characterized by high plasma and urinary ieveis of homocysteine and methionine, and low levels of cysteine. T . . .

The purpose of this study is to determine whether the level of folic acid (FA) in human blood serum affects the number of fragile sites observed in cultured T-lymphocytes. Private practice patients (Internal Medicine) who evidenced no symptoms of sign . . .

Iranian Jews constitute a growing minority in metropolitan cities around the United States. They are part of a close-knit community, with strong family and cultural values. Prevailing negative attitudes in the Iranian Jewish society towards disease an . . .

Cell adhesion has been studied for almost a century beginning with H.V. Wilson's classic studies on sponge cell aggregation. Cell adhesion plays an important role in morphogenesis and malignancy, but its molecular basis is poorly understood. As the ce . . .

The sea urchin is the material of choice for studying many early developmental events. Methods to extend the viability of sea urchin gametes have not received much attention, but it is well known that the eggs are easily damaged by freezing (4). This . . .

Many studies have examined the effects of free lectins such as Concanavalin-A (Con-A) on sea urchin development and suggested that lectin binding ligands play a role in embryonic cellular interactions. In this study, the effects of immobilized Con-A o . . .