Apoptosis is the cell’s primary response to stress, and is one of the body’s most important lines of defense against cancer. The process is initiated and governed by the Bcl-2 family of regulatory proteins, which contains both pro- and anti-apoptotic . . .

The Bcl-2 protein family, made up of pro and anti-apoptotic proteins plays a major role in regulating apoptosis. Bax is a pro-apoptotic member of the Bcl-2 family. In its inactive form, Bax is primarily a cytosolic and monomeric protein. Upon activati . . .