ArticleChen, WeiIn cardiac myocytes, calcium (Ca) can be released from the sarcoplasmic reticulum independently of Ca influx from voltage-dependent membrane channels. This efflux of Ca, referred to as spontaneous Ca release (SCR), is due to Ryanodine receptor fluctua . . .
ArticleVariability In Timing Of Spontaneous Calcium Release In The Intact Rat Heart Is Determined By The Time Course Of Sarcoplasmic Reticulum Calcium LoadPatel, HeetabhBackground: Abnormalities in intracellular calcium (Ca) cycling during Ca overload can cause triggered activity because spontaneous calcium release (SCR) activates sufficient Ca-sensitive inward currents to induce delayed afterdepolarizations (DADs). . . .