ProjectGeneration of liver organoids using IPSC derived hepatocyte and endothelial cells for persistent secretion of factor VIIICortez-Toledo, Elizabeth JasminHemophilia A (HA) is a genetic disorder resulting from deficient levels of the coagulation protein factor VIII. HA is inherited through an X-linked recessive pattern and is characterized clinically by excessive and spontaneous bleeding, the severity o . . .
ProjectHyllen, Alicia AnnHemophilia A (HA) is an X-linked disorder that occurs in 1 in 5,000 male births. A lack of the blood clotting protein factor VIII (FVIII) in the blood plasma in HA patients due to mutations in the F8 gene results in excessive and prolonged hemorrhage. . . .