A series of N-monosubstituted and N,N'-disubstituted derivatives of the indolo[3,2-b]carbazole chromophore have been prepared, and their binding affinity for duplex DNA has been evaluated by ultraviolet and fluorescence spectroscopies. It has been fou . . .

We show that the cAMP receptor protein (Crp) binds to DNA as several different conformers. This situation has precluded discovering a high correlation between any sequence property and binding affinity for proteins that bend DNA. Experimentally quanti . . .

Plant cells are incapable of sliding past each other, so generation of shape and structure in plant tissue is dependent on cells dividing and expanding in particular directions. Therefore, understanding how cells choose where to build new walls is cri . . .

The spread of C4 grasses in the late Neogene is one of the most important ecological transitions of the Cenozoic, but the primary driver of this global expansion is widely debated. We use the stable carbon isotopic composition (δ13C) of bison and mamm . . .

The transition from middle school to high school is an important developmental period to investigate because of the negative impact it has on youths' academics. The purpose of this study was to investigate Latino youths' academic achievement prior to, . . .

An unexplained residual in the fits of theoretical and experimental spectra of exchange broadened nitroxide spin probes reported by Robinson et al. [J. Magn. Reson. 138 (1999) 199] is shown to be understood by inclusion of theoretically predicted line . . .

A new approach is presented for determining the rigid regions in proteins and the flexible joints between them. The short-range forces in proteins are modeled as constraints and we use a recently developed formalism from graph theory to analyze flexib . . .

AdoMet radical enzymes are involved in processes such as cofactor biosynthesis, anaerobic metabolism, and natural product biosynthesis. These enzymes utilize the reductive cleavage of S-adenosylmethionine (AdoMet) to afford L-methionine and a transien . . .

We model the hierarchical evolution of an organized criminal network via antagonistic recruitment and pursuit processes. Within the recruitment phase, a criminal kingpin enlists new members into the network, who in turn seek out other affiliates. New . . .

Using cross-sectional data, we examined the financial information sources, financial knowledge, and financial practices of young adults, many of whom are first generation college students, ethnic minorities, and immigrants or children of immigrants. P . . .