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ArticleRoberson, MarieMORPHOGENESIS and malignant invasion seem to be dependent on cellular migration and changes in cellular adhesiveness1-3. Plant lectins such as concanavalin A (con A) have been extensively used to study the nature and distribution of lectin receptor si . . .
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ArticleOppenheimer, Steven B.For decades it has been assumed that in order to insert macromolecules into the embryo blastocoel for numerous experimental purposes, microinjection was required. Microinjection, however, can be only performed on a few embryos at a time, thus precludi . . .
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ArticleOppenheimer, Steven B.Many studies have examined the effects of lectins on embryonic development. Recently, it has been shown that lectins actually enter the blastocoel of sea urchin embryos without microinjection and bind to specific cell types. The present study was perf . . .
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ArticleOppenheimer, Steven B.For over a decade our laboratory has developed and used a novel histochemical assay using derivatized agarose beads to examine the surface properties of various cell types. Most recently, we have used this assay to examine lectin binding ligands on tw . . .
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ArticleOppenheimer, Steven B.This chapter discusses the interactions of lectins with embryonic cell surfaces. It summarizes the information on various lectins and their sugar-binding specificity deals with the information gained through the study of the interactions of lectins wi . . .
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ThesisKatchikian, HurigA superior mechanism of detecting cancerous cells and delivering anti-cancer drugs to highly localized targets is currently lacking in the field of oncology. Unfortunately, chemotherapy is not a specialized method of delivering therapeutic reagents to . . .
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ArticleOppenheimer, Steven B.We have previously developed a novel method to determine the presence or absence of cell surface lectin receptors using derivatized agarose beads and have used many different derivatized beads in examining other cell surface properties. Thus, we have . . .