ThesisTransplantation of human neural progenitor cells reveals structural and functional improvements in the spastic han-wistar rat model of ataxiaNuryyev, RuslanBackground: In this study, we assessed the ability of human neural progenitor cells (hNPC) to repair and restore the function of dying neurons within the spastic Han-Wistar rat (sHW), the mutant variant of a normal Han-Wistar. The sHW rat suffers from . . .
ArticleChronic Leptin Treatment Enhances Insulin-Stimulated Glucose Disposal In Skeletal Muscle Of High-Fat Fed RodentsKrisan, Adam DThe aim of this investigation was to evaluate if chronic leptin administration corrects high fat diet-induced skeletal muscle insulin resistance, in part, by enhancing rates of glucose disposal and if the improvements are accounted for by alterations . . .
ArticleLipid-induced mTOR activation in rat skeletal muscle reversed by exercise and 5"�-aminoimidazole-4-carboxamide-1-β-D-ribofuranosideHawley, J.AThe serine/threonine protein kinase, mammalian target of rapamycin (mTOR) is regulated by insulin and nutrient availability and has been proposed to play a central role as a nutrient sensor in skeletal muscle. mTOR associates with its binding partners . . .