Article

P6-12:Spatially discordant alternans emerges in the absence of conduction velocity involvement in myocyte monolayers

In homogenous tissue, conduction velocity restitution (CVR) is required for the development of spatially discordant alternans (SDA) except after an ectopic beat. We hypothesized that global capture of monolayers would eliminate CV gradients and SDA would arise from calcium (Ca) dynamics in the absence of CVR involvement.

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