Study Design of the Maycoba Project: Obesity and Diabetes in Mexican Pimas

Objective: To focus on the rationale and methods of the Maycoba Project. Methods: Study population included Mexican Pima Indians (MPI) and Blancos aged ≥20-years, living in the village of Maycoba and surrounding area. Surveys in 1995 and 2010 included a medical history, biochemical and anthropomet- ric measurements. Additionally, socio- economic, physical activity, and dietary interviews were conducted. The 2010 study incorporated investigations on type 2 diabetes (T2D) and obesity-associated genetic alleles and human-envi- ronment changes. Results: The study results are limited to demographic data and description of the eligible and ex- amined sample. Conclusions: This study may yield important information on T2D and obesity etiology in a traditional population exposed to environmental changes.