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Genetic influences on the development of aggressive behaviors in mice.
Aggressive behavior in mice has been the focus of intense study for a number of decades. Over thirty years ago, Uhrich (1938) after observing 450 mice concluded that aggressive behaviors are influenced by a variety of factors. He found that the animal's sex, weight, and previous life experiences were of importance in determining which animal would attack and fight another. He also concluded that the location and time of testing were important. These findings might have given other researchers a clue that the components of aggressive behavior are complex and could best be examined using a multifaceted approach. Yet, with seeming ignorance, research on aggression in mice has developed almost exclusively along two separate and distinct lines.