Effect of hormone replacement therapy on implicit and explicit memory in post-menopausal women
The present study looked at the effect of hormone replacement therapy (HRT) on implicit and explicit memory test performance in post-menopausal women (N = 60). Women who were either on HRT (n = 20), had previously been on HRT (n = 20), or had never been on HRT (n = 20) were recruited from local residents of Stanislaus, San Joaquin, Sacramento, and Tuolumne counties. Explicit memory was measured using the Logical Memory subtest of the Wechsler Memory Scale. Implicit memory was measured using one of four stem completion tests that were counterbalanced across conditions and used low-frequency words. It was hypothesized that the HRT group would outperform the previous-HRT and non-HRT group on both tests. Results fully supported the hypothesis. A significant negative correlation was noted between age and implicit, but not explicit, scores. These findings suggest that HRT may have useful role in enhancing explicit and implicit memory in post-menopausal women.