Thesis

The taxonomic status of Haemophilus aphrophilus: a study using transformation

Beattie and Setlow (1970) presented data to expand and confirm the "lethality mechanism" theory. Steinhart and Herriott (1968b) noted that their theory need not necessarily replace Schaeffer's "limited pairing" hypothesis since the integration level in their heterospecific transformation studies was only 48 to 78$, not 100$, of the homospecific level. Schaeffer (1958) had postulated that low transformation results may be due to the lack of structural identity between donor and recipient DNA, resulting in imperfect pairing. The present project was an attempt to determine whether sufficient chromosomal similarity exists to warrant the present taxonomic status of H. aphrophilus as a member of the genus Haemophilus.

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