Masters Thesis

Endotoxin of Erwinia herbicola.

Shortly after the discovery of the role of bacteria as the etiological agents of human disease, the search for bacterial toxins began. Bacterial toxins were an important discovery, because they may enhance the pathogenicity of infection; the effect of toxins on pathogenicity depends upon the infecting microorganism, the dose, and the route of injection, as well as the interval between the administration of the toxin and the initiation of infection.