Thesis

Relationship between intercellular adhesiveness and glutamine synthetase specific activity in synchronized cultures of mouse teratoma cells

In cultures of mouse teratoma, cells synchronized with thymidine (3mM) and colcemid (0.5 mcg/ml), cellular adhesiveness displayed an oscillatory pattern with peaks of glutamine synthtase (GS} specific activity occurring lust prior to peaks of adhesiveness. The results demonstrate a correlation between GS specific activity and cellular adhesiveness. Based upon previous work which implies L.-glutamine in intercellular adhesion, it is not unreasonable to speculate that GS specific activity and cellular adhesiveness may be causally related.

Le relazioni

Elementi